Is Tobacco Use Associated with Neurocognitive Dysfunction in Individuals with HIV?

Is Tobacco Use Associated with Neurocognitive Dysfunction in Individuals with HIV?

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Introduction: sources iphone 90m The prevalence of HIV-associated neurocognitive disorders continues to rise despite the widespread use of antiretroviral therapy.We aimed to define the risk of neurocognitive dysfunction among smokers relative to nonsmokers.Methods: We conducted a retrospective cohort study including HIV-infected adults ages 21 to 65 years.

The Mental Alternation Test (MAT) was the primary outcome.The odds of cognitive impairment were compared using random-effects logistic regression to adjust for potential confounders.Results: Of 3033, 1486 (49%) were smokers.

The odds ratio for the association between smoking and cognitive impairment was 1.12 (95% confidence interval: 0.85-1.

49).Nonsmokers had a higher median MAT score relative to smokers ( P =.01).

Conclusion: There was no evidence that HIV-infected smokers had greater neurocognitive dysfunction relative to HIV-infected nonsmokers.While tobacco use remains an important health risk issue to address in the HIV population, it may enchanted wonderstruck perfume not represent a risk factor for neurocognitive impairment.